Basic Information
| Product Name | Mangiferin |
|---|---|
| Synonym | Null |
| Latin Name | Mangifera indica L. |
| CAS Number | 4773-96-0 |
| Part Used | Leaf |
| Origin | China |
| Trademark | JINGMU |
| HS Code | 2942000000 |
| Grade | Food Grade |
| Appearance | Yellow Powder |
| Specification | 95%, 98% |
| Solubility | Slightly soluble in waterwater |
| Test Method | HPLC |
| Free Sample | 20g or 50g is avaliable |
| Production Capacity | 2 Tons/Month |
Description
Mangiferin is a bioactive xanthone glycoside primarily extracted from the leaves, bark, and fruit kernels of the mango tree (Mangifera indica), a plant deeply rooted in traditional medicine across Asia and Africa. This compound is concentrated using advanced extraction techniques to yield a fine, yellow crystalline powder. Mangiferin is celebrated for its potent antioxidant, anti-inflammatory, and metabolic regulatory properties, underpinning its diverse health applications.
Mangiferin is extensively utilized in pharmaceuticals, nutraceuticals, functional foods, beverages, and skincare products. Recent research highlights its potential in managing metabolic disorders, inflammatory conditions, oxidative stress-related damage, and skin health. Preliminary studies also suggest benefits for liver protection, neuroprotection, and immune modulation.
Function
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Potent Antioxidant Activity
Mangiferin directly scavenges free radicals (e.g., hydroxyl and superoxide radicals), inhibits lipid peroxidation, and enhances endogenous antioxidant systems (e.g., glutathione, superoxide dismutase). This shields cells from oxidative damage linked to aging, chronic diseases, and environmental stressors. -
Anti-Inflammatory Action
It suppresses pro-inflammatory cytokines (e.g., TNF-α, IL-6) and inhibits enzymes like COX-2 and iNOS. This mitigates chronic inflammation associated with arthritis, metabolic syndrome, and neurodegenerative disorders. -
Metabolic Health Support
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Blood Sugar Regulation: Enhances insulin sensitivity, activates AMPK pathways, and inhibits carbohydrate-digesting enzymes (α-amylase/α-glucosidase), aiding glycemic control in diabetes.
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Lipid Metabolism: Reduces serum triglycerides and LDL cholesterol while elevating HDL, improving overall lipid profiles.
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Liver Protection (Hepatoprotective)
Mangiferin shields hepatocytes from toxins (e.g., alcohol, acetaminophen), reduces fatty liver accumulation, and combats hepatic fibrosis by modulating inflammation and oxidative stress pathways. -
Neuroprotective Potential
Crosses the blood-brain barrier to reduce neuroinflammation, inhibit acetylcholinesterase (enhancing cognition), and protect neurons from oxidative damage. Studied for roles in Alzheimer’s and Parkinson’s disease management. -
Cardiovascular Benefits
Improves endothelial function, reduces arterial plaque formation, and lowers blood pressure via antioxidant and anti-inflammatory mechanisms, supporting heart health. -
Immune System Modulation
Enhances innate and adaptive immune responses by regulating macrophage activity and T-cell differentiation, offering adjuvant therapy potential.
Application
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Anti-Aging & Skin Repair:
Neutralizes UV-induced free radicals, boosts collagen synthesis, and inhibits matrix metalloproteinases (MMPs) to reduce wrinkles and improve skin elasticity. -
Brightening & Hyperpigmentation Control:
Inhibits tyrosinase activity, reducing melanin production for a more even skin tone. -
Anti-Inflammatory Care:
Calms irritated or acne-prone skin by reducing redness and swelling.
