Basic Information
| Product Name | Taxifolin / Astilbin |
|---|---|
| Synonym | Null |
| Latin Name | Engelhardia roxburghiana |
| CAS Number | 480-18-2 / 29838-67-3 |
| Part Used | Leaf |
| Origin | China |
| Trademark | JINGMU |
| HS Code | 2932999099 |
| Grade | Food Grade |
| Appearance | Yellow Powder / White powder |
| Specification | 98% |
| Solubility | very slightly soluble or slightly soluble in water |
| Test Method | HPLC |
| Free Sample | 20g or 50g is avaliable |
| Production Capacity | 2 Tons/Month |
Description
Taxifolin and Astilbin Extract is derived from the leaves of the Engelhardia roxburghiana tree, a plant traditionally used in Asian herbal medicine. This extract is standardized to contain ≥98% Taxifolin (Dihydroquercetin) and Astilbin, two potent bioactive compounds. Through advanced extraction and purification processes, it yields a fine, light-yellow to off-white powder with high solubility and bioavailability.
Function
1. Potent Antioxidant & Anti-Aging Effects
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Scavenges Free Radicals: Taxifolin and Astilbin neutralize reactive oxygen species (ROS), lipid peroxides, and alkyl radicals, protecting cells from oxidative stress.
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Inhibits Lipid Peroxidation: Protects cellular membranes and mitochondrial integrity, slowing aging processes and reducing UV-induced skin damage.
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Cosmetic Applications: Used in anti-aging serums, whitening creams, and sunscreens to combat wrinkles, hyperpigmentation, and photoaging.
2. Cardiovascular & Metabolic Support
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Vasoprotective Action: Strengthens capillary walls, reduces vascular permeability, and improves microcirculation.
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Anti-Atherogenic: Lowers LDL oxidation and regulates blood lipid profiles, preventing atherosclerosis.
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Anti-Hyperuricemic (Astilbin): Inhibits xanthine oxidase, reducing uric acid levels and alleviating gout symptoms.
3. Anti-Inflammatory & Immunomodulatory Effects
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Suppresses Pro-Inflammatory Cytokines: Downregulates TNF-α, IL-6, and NF-κB pathways, mitigating chronic inflammation.
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Autoimmune Support (Astilbin): Modulates T-cell activity and immune responses, beneficial for rheumatoid arthritis and allergies.
4. Hepatorenal Protection
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Detoxification Aid: Taxifolin enhances glutathione synthesis and phase II liver detox enzymes, shielding against hepatotoxins (e.g., alcohol, heavy metals).
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Renal Anti-Fibrosis (Astilbin): Reduces kidney fibrosis and oxidative stress in diabetic nephropathy.
5. Neuroprotective & Cognitive Benefits
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Blood-Brain Barrier Penetration: Taxifolin crosses the BBB, quenching neuronal oxidative stress and amyloid-β toxicity.
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Memory Enhancement: Improves synaptic plasticity and cerebral blood flow, supporting cognitive function in age-related decline.
Application
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Pharmaceuticals: Formulated for treating gout, metabolic syndrome, liver disorders, and neurodegenerative conditions.
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Nutraceuticals: Capsules/powders for antioxidant support, anti-inflammation, and uric acid management.
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Cosmeceuticals: Key ingredient in anti-aging creams, brightening toners, and protective lotions.
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Functional Foods/Beverages: Added to health drinks and supplements for systemic wellness.
