Basic Information
| Product Name | Andrographis Paniculate Extract |
|---|---|
| Synonym | Andrographis Extract |
| Latin Name | Andrographis paniculata (Burm. f.) Nees |
| CAS Number | 5508-58-7 |
| Part Used | Whole Herb |
| Origin | China |
| Trademark | JINGMU |
| HS Code | 1302199099 |
| Grade | Food Grade |
| Appearance | Brown Powder |
| Specification | 50%-95% Andrographolide |
| Solubility | Water Soluble |
| Test Method | HPLC |
| Free Sample | 20g or 50g is avaliable |
| Production Capacity | 2 Tons/Month |
Description
Andrographolide, the primary bioactive compound in Andrographis paniculata (commonly known as “King of Bitters”), is renowned for its multifaceted therapeutic properties. Modern scientific studies validate that over 70% of the plant’s health benefits stem from andrographolide, which constitutes 10%-30% of the extract’s total diterpene lactone content. This potent compound exhibits anti-inflammatory and immunomodulatory activities 20-50 times stronger than common herbal alternatives like echinacea. Derived through advanced extraction techniques, andrographolide is a water-soluble, highly stable molecule with a unique bicyclic diterpenoid structure. Its mechanism of action includes modulating NF-κB signaling pathways, making it a critical agent in combating chronic inflammation, viral infections, and immune dysregulation. Furthermore, its hepatoprotective properties and ability to enhance detoxification enzymes position it as a cornerstone in modern herbal pharmacology.
Function
Andrographolide stands as a powerhouse of natural healing, offering unparalleled benefits across immune support, metabolic health, and cellular protection. As a broad-spectrum immune enhancer, it stimulates antibody production and macrophage activity, fortifying the body’s defenses against pathogens. Its antiviral prowess is clinically proven against influenza, dengue, and even SARS-CoV-2, inhibiting viral replication at early stages. In metabolic health, andrographolide demonstrates hypoglycemic effects by improving insulin sensitivity and reducing hepatic glucose output, making it invaluable for diabetes management.
Notably, its anti-inflammatory and antioxidant synergy surpasses synthetic alternatives, effectively mitigating oxidative stress linked to neurodegenerative diseases and aging. For skin health, andrographolide accelerates wound healing, reduces acne via antibacterial action, and protects against UV-induced collagen degradation. Additionally, it supports cardiovascular resilience by lowering LDL oxidation and improving endothelial function, while its hepatorenal protective effects aid in toxin clearance and organ regeneration.
Application
This extract is standardized to 50%-98% andrographolide content, presented as a fine, off-white to light-yellow powder with minimal bitter aftertaste—a breakthrough in masking the plant’s inherent pungency. Its exceptional stability ensures compatibility with hot-fill beverages, effervescent tablets, and topical emulsions without degradation. As a caffeine-free, non-GMO ingredient, it meets clean-label demands across vegan, paleo, and ketogenic markets. Cost-efficient compared to synthetic immune modulators, it offers superior bioavailability through nanoemulsion and liposomal delivery systems.
